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Article

Advanced onset of menarche and higher bone mineral density depending on vitamin D receptor gene polymorphism.

European journal of endocrinology - 1 Nov 1998

Kitagawa I, Kitagawa Y, Kawase Y, Nagaya T, Tokudome S

Abstract excerpt

Bone mineral density (BMD) at distal forearm, and weight and height of healthy Japanese girls aged 18-19 years were measured and their age at menarche was obtained through a questionnaire. A statistically significant association was found between BMD at distal radius and vitamin D receptor (VDR) gene polymorphism at the ApaI site. The age at menarche in the population with Aa genotype was significantly earlier...

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Source

Identifiers

PMID: 9849817
DOI: 10.1530/eje.0.1390522

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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