[Genetic and molecular diagnostics in retinoblastoma].

doi:10.1055/s-2008-1034972

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Article

[Genetic and molecular diagnostics in retinoblastoma].

Klinische Monatsblatter fur Augenheilkunde - 1 Oct 1998

Lohmann D, Horsthemke B

Abstract excerpt

Retinoblastoma is a childhood malignancy of the eye. Almost all patients with familial or bilateral disease suffer from the hereditary form of the disease that is caused by germline mutations in one allele of the RB1 gene. Tumor development is initiated by the loss of the second RB allele in a re...

Topics

Female
Genetic Predisposition to Disease
Genetic Testing
Humans
Male
Pedigree
Retinoblastoma

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