Article
The structure and organization of the human carnitine/acylcarnitine translocase (CACT1) gene2.
Biochemical and biophysical research communications - 27 Nov 1998
Iacobazzi V, Naglieri M A, Stanley C A, Wanders R J, Palmieri F
Abstract excerpt
The carnitine/acylcarnitine translocase (CACT) transports acylcarnitines into mitochondria in exchange for free carnitine and it is, therefore, essential for the fatty acid beta-oxidation pathway. We have determined the exon-intron structure of the human CACT gene, which is responsible for a gene...
Topics
- Carnitine Acyltransferases
- Cloning, Molecular
- DNA Mutational Analysis
- DNA Primers
- Exons
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Polymerase Chain Reaction
- Sequence Deletion