Article
MSX1 gene polymorphisms in Mexican patients with non-syndromic cleft lip/palate.
International journal of pediatric otorhinolaryngology - 1 Nov 2016
Ibarra-Arce Aurora, Albavera-Giles Tania, Zavaleta-Villa Beatriz, Ortiz de Zárate-Alarcón Gabriela, Flores-Peña Laura, Sierra-Romero María Del Carmen, Romero-Valdovinos Mirza, Olivo-Díaz Angélica
Abstract excerpt
OBJECTIVE: Non-syndromic cleft lip/palate malformation (CL/P) is one of the most common birth defects in humans and has a complex etiology involving genetic and environmental factors. Mutations in the MSX1 gene are critical during craniofacial development. The purpose of this study was to investigate the contribution of MSX1 gene polymorphisms to the risk of developing CL/P in a sample of Mexican patients....
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