Article
[Susceptibility to neuro-malaria and HLA-DR alleles in Senegal].
Dakar medical - 1 Jan 1998
Ndiaye M, Thiam A, Ndiaye R, Angel G, Seignot P, Roussilhon C, Sarthou J L, Dieye A
Abstract excerpt
A prospective study was carried out in 46 patients suffering from severe malaria. The control group included 220 persons of which the HLA-DR distribution was known. The HLA-DRB1 alleles were typed by PCR-SSP (Sequence Specific Primers). The most frequent HLA-DR alleles found in patients group wer...
Topics
- Adult
- Alleles
- Child
- Coma
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Glasgow Coma Scale
- HLA-DR Antigens
- Humans
- Malaria, Falciparum
- Male
- Risk
- Senegal
