Article
[Susceptibility to neuro-malaria and HLA-DR alleles in Senegal].
Dakar medical - 1 Jan 1998
Ndiaye M, Thiam A, Ndiaye R, Angel G, Seignot P, Roussilhon C, Sarthou J L, Dieye A
Abstract excerpt
A prospective study was carried out in 46 patients suffering from severe malaria. The control group included 220 persons of which the HLA-DR distribution was known. The HLA-DRB1 alleles were typed by PCR-SSP (Sequence Specific Primers). The most frequent HLA-DR alleles found in patients group were: DR52 (82.8%), DR13 (57.1%), DR10 (28.6%), DR53 (25.7%), DR3 (20%), DR18 (20%). A significant difference was observed...
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