The cardiac beta-myosin heavy chain gene is not the predominant gene for hypertrophic cardiomyopathy in the Finnish population.

doi:10.1016/s0735-1097(98)00448-3

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Article

The cardiac beta-myosin heavy chain gene is not the predominant gene for hypertrophic cardiomyopathy in the Finnish population.

Journal of the American College of Cardiology - 15 Nov 1998

Jääskeläinen P, Soranta M, Miettinen R, Saarinen L, Pihlajamäki J, Silvennoinen K, Tikanoja T, Laakso M, Kuusisto J

Abstract excerpt

OBJECTIVES: The aim of the study was to screen 36 unrelated patients with hypertrophic cardiomyopathy (HCM; 16 familial and 20 sporadic cases) from a genetically homogeneous area in eastern Finland for variants in the cardiac beta-myosin heavy chain (beta-MHC) and alpha-tropomyosin (alpha-TM) gen...

Topics

Amino Acid Substitution
Base Sequence
Cardiomyopathy, Hypertrophic
Female
Finland
Genetic Linkage
Genetic Variation
Humans
Male
Middle Aged
Mutation, Missense
Myocardium
Myosin Heavy Chains
Pedigree
Tropomyosin

Source

Open in PubMed

Identifiers

PMID: 9822100
DOI: 10.1016/s0735-1097(98)00448-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9822100-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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