Article
Evidence of genetic heterogeneity of hypertrophic cardiomyopathy in eight Chinese patients.
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed - 1 May 1996
Hwang D S, Chen Y T, Su J S, Hu W H, Wang K Y, Ting C T
Abstract excerpt
BACKGROUND: The genetic basis causing hypertrophic cardiomyopathy (HCM) was found due to missense mutations in cardiac beta-myosin heavy chain (beta-MHC), cardiac troponin T and alpha-tropomyosin genes in certain affected families. However, most mutations and majority of the affected families wer...
Topics
- Aged
- Aged, 80 and over
- Base Sequence
- Cardiomyopathy, Hypertrophic
- Female
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Myosin Heavy Chains
- Pedigree
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Taiwan