Larger CAG expansions in skeletal muscle compared with lymphocytes in Kennedy disease but not in Huntington disease.

doi:10.1212/wnl.51.5.1442

Back to search

Article

Larger CAG expansions in skeletal muscle compared with lymphocytes in Kennedy disease but not in Huntington disease.

Neurology - 1 Nov 1998

Ansved T, Lundin A, Anvret M

Abstract excerpt

The size of CAG repeats was compared in lymphocytes and skeletal muscle from nine patients with Huntington disease (HD) and two patients with Kennedy disease (KD). In HD, the number of CAG repeats did not differ between lymphocytes and skeletal muscle. In the two KD patients, however, the CAG exp...

Topics

Aged
Alleles
Genetic Carrier Screening
Humans
Huntington Disease
Lymphocytes
Middle Aged
Muscle, Skeletal
Muscular Atrophy, Spinal
Organ Specificity
Trinucleotide Repeats

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.