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Article

A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum.

The Journal of cell biology - 16 Nov 1998

Silberstein S, Schlenstedt G, Silver P A, Gilmore R

Abstract excerpt

Members of the eukaryotic heat shock protein 70 family (Hsp70s) are regulated by protein cofactors that contain domains homologous to bacterial DnaJ. Of the three DnaJ homologues in the yeast rough endoplasmic reticulum (RER; Scj1p, Sec63p, and Jem1p), Scj1p is most closely related to DnaJ, hence it is a probable cofactor for Kar2p, the major Hsp70 in the yeast RER. However, the physiological role of Scj1p has...

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Identifiers

PMID: 9817751
DOI: 10.1083/jcb.143.4.921
PMCID: PMC2132949

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