Serial isolates of Cryptococcus neoformans from patients with AIDS differ in virulence for mice.

doi:10.1086/314521

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Article

Serial isolates of Cryptococcus neoformans from patients with AIDS differ in virulence for mice.

The Journal of infectious diseases - 1 Dec 1998

Fries B C, Casadevall A

Abstract excerpt

Serial isolates of Cryptococcus neoformans from patients with chronic infection can exhibit minor karyotype changes as a result of chromosome length polymorphism (CLP). This study investigated whether serial C. neoformans isolates with CLP from 4 patients with AIDS exhibited biologic and phenotyp...

Topics

AIDS-Related Opportunistic Infections
Animals
Chromosomes, Bacterial
Cryptococcosis
Cryptococcus neoformans
Humans
Karyotyping
Mice
Phenotype
Polymorphism, Genetic
Species Specificity
Virulence

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