The impact of molecular diagnosis on familial colorectal cancer.

doi:10.1515/CCLM.1998.113

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Article

The impact of molecular diagnosis on familial colorectal cancer.

Clinical chemistry and laboratory medicine - 1 Aug 1998

Bennett G, Rudzki Z, Cole S, Young G, Suthers G

Abstract excerpt

We have shown the impact of molecular diagnostics related to mutation detection in an extensive family with a strong history of colorectal cancer. The nature and presentation of the cancers suggested that hereditary nonpolyposis colorectal cancer was the most likely cause. The strategies employed...

Topics

Adaptor Proteins, Signal Transducing
Base Sequence
Carrier Proteins
Colorectal Neoplasms
DNA Primers
DNA-Binding Proteins
Female
Genetic Counseling
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

MutL Protein Homolog 1

MutS Homolog 2 Protein

Neoplasm Proteins

Nuclear Proteins

Pedigree

Proto-Oncogene Proteins

Source

Open in PubMed

Identifiers

PMID: 9806477
DOI: 10.1515/CCLM.1998.113

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9806477-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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