Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency.

Tissue antigens - 1 Sept 1998

Clavijo O P, Delgado J C, Awdeh Z L, Fici D, Turbay D, Alper C A, Truedsson L, Yunis E J

Abstract excerpt

There are four MHC-linked complement genes, BF, C2, C4A and C4B, that are inherited as single DNA units, known as complotypes. Extended haplotypes were initially defined by studying the distribution of complotypes in relation to HLA-B and HLA-DR loci in Caucasian families. In order to analyze the...

Topics

Alleles
Complement C2
Genetic Linkage
Genetic Testing
HLA Antigens
HLA-C Antigens
Haplotypes
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
White People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9802610
DOI: 10.1111/j.1399-0039.1998.tb03045.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9802610-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency.PMID 9802610Read ↗

Complotypes in individuals of African origin: frequencies and possible extended MHC haplotypes.Semantic proximity Read ↗

Characterization of type I complement C2 deficiency MHC haplotypes. Strong conservation of the complotype/HLA-B-region and absence of disease association due to linked class II genes.Semantic proximity Read ↗

Allelic associations of multiple RFLPs of the gene encoding complement protein C2.Semantic proximity Read ↗

HLA-Cw allele analysis by PCR-restriction fragment length polymorphism: study of known and additional alleles.Semantic proximity Read ↗

Association of polymorphisms in the HLA-B region with extended haplotypes.Semantic proximity Read ↗

Two different complement Factor B (Bf) alleles of the orangutan major histocompatibility complex (MHC) are also conserved in chimpanzee and humans showing importance in primate immunity.Semantic proximity Read ↗

Type I human complement C2 deficiency. A 28-base pair gene deletion causes skipping of exon 6 during RNA splicing.Semantic proximity Read ↗

Allelic polymorphism of two multifunctional regions in the central human MHC: tenascin X, XB-S and YB, and their duplicated fragments XA and YA.Semantic proximity Read ↗

Frequency in Spanish population of familial complement factor 2 type I deficits and associated HLA haplotypes.Semantic proximity Read ↗

Combined heterozygous deficiency of the classical complement pathway proteins C2 and C4.Semantic proximity Read ↗

A decrease in the estimated frequency of the extended HLA haplotype B18 CF130 DR3 DQw2 is common to non-insulin-dependent diabetes, juvenile rheumatoid arthritis, and Berger's disease.Semantic proximity Read ↗

High-allelic variability in HLA-C mRNA expression: association with HLA-extended haplotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.