Article
HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency.
Tissue antigens - 1 Sept 1998
Clavijo O P, Delgado J C, Awdeh Z L, Fici D, Turbay D, Alper C A, Truedsson L, Yunis E J
Abstract excerpt
There are four MHC-linked complement genes, BF, C2, C4A and C4B, that are inherited as single DNA units, known as complotypes. Extended haplotypes were initially defined by studying the distribution of complotypes in relation to HLA-B and HLA-DR loci in Caucasian families. In order to analyze the distribution of HLA-Cw alleles in relation to extended haplotypes, we studied a large panel of MHC homozygous and...
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