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Article

Hemoglobins in Togolese newborns: Hb S, Hb C, Hb Bart's, and alpha-globin gene status.

American journal of hematology - 1 Nov 1998

Segbena A Y, Prehu C, Wajcman H, Bardakdjian-Michau J, Messie K, Feteke L, Vovor A, David M, Feingold J, Galacteros F

Abstract excerpt

The gene frequency of the most important hemoglobin (Hb) abnormalities is reported in a population of 171 Togolese newborns. Hb phenotypes, hematological parameters, and the more frequently described alpha-gene deletions were analyzed. Structural abnormalities of beta-globin were observed in 35.7% of the children with a gene frequency of 0.105 for beta(S) and 0.091 for beta(C). The frequency of the different...

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Identifiers

PMID: 9798658
DOI: 10.1002/(sici)1096-8652(199811)59:3<208::aid-ajh5>3.0.co;2-r

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