Noninsulin-dependent diabetes mellitus as a mitochondrial genomic disease.

doi:10.3181/00379727-219-44321

Article

Noninsulin-dependent diabetes mellitus as a mitochondrial genomic disease.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) - 1 Nov 1998

Mathews C E, Berdanier C D

Abstract excerpt

The genetics of diabetes mellitus is very complex. Although the phenotypes are relatively simple vis-a-vis an abnormal glucose-insulin relationship, a number of genotypes share this phenotype. This review focuses on mutations in the mitochondrial genome that phenotype as diabetes mellitus. Studie...

Topics

Animals
DNA, Mitochondrial
Diabetes Mellitus, Type 2
Genome, Human
Humans
Mitochondria
Mutation
Rats

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