Article
Noninsulin-dependent diabetes mellitus as a mitochondrial genomic disease.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) - 1 Nov 1998
Mathews C E, Berdanier C D
Abstract excerpt
The genetics of diabetes mellitus is very complex. Although the phenotypes are relatively simple vis-a-vis an abnormal glucose-insulin relationship, a number of genotypes share this phenotype. This review focuses on mutations in the mitochondrial genome that phenotype as diabetes mellitus. Studies in the human and the rat are described.
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