Article
Cats are protected against feline immunodeficiency virus infection following vaccination with a homologous AP-1 binding site-deleted mutant.
Archives of virology - 1 Jan 1998
Kohmoto M, Miyazawa T, Sato E, Uetsuka K, Nishimura Y, Ikeda Y, Inada G, Doi K, Mikami T
Abstract excerpt
Following establishment, via the vaginal route, of infection with an AP-1 binding-site deleted mutant (delta AP-1) of feline immunodeficiency virus (FIV), cats were challenged with a homologous intact strain (TM2) of FIV. The cats were observed for 23 weeks to evaluate the efficacy of the delta A...
Topics
- Animals
- Binding Sites
- Cats
- DNA, Viral
- Feline Acquired Immunodeficiency Syndrome
- Female
- Mutation
- Polymerase Chain Reaction
- Proviruses
- Transcription Factor AP-1
- Vaccination
- Vaginal Diseases
- Viral Vaccines