Article
Metabolic routing towards polyhydroxyalkanoic acid synthesis in recombinant Escherichia coli (fadR): inhibition of fatty acid beta-oxidation by acrylic acid.
FEMS microbiology letters - 1 Oct 1998
Qi Q, Steinbüchel A, Rehm B H
Abstract excerpt
Heterologous expression of the phaC1 gene from Pseudomonas aeruginosa, which encodes one of the polyhydroxyalkanoic acid synthases, in Escherichia coli impaired in fatty acid beta-oxidation results in polyhydroxyalkanoic acid accumulation when cells were cultivated on fatty acids. We evaluated th...
Topics
- Acrylates
- Acyltransferases
- Bacterial Proteins
- Carboxylic Acids
- Escherichia coli
- Fatty Acids
- Fermentation
- Genes, Bacterial
- Mutation
- Oxidation-Reduction
- Plasmids
- Pseudomonas aeruginosa
- Recombination, Genetic
- Repressor Proteins