Article
Virus-receptor interactions and interspecies transfer of a mouse hepatitis virus.
Advances in experimental medicine and biology - 1 Jan 1998
Hensley L E, Holmes K V, Beauchemin N, Baric R S
Abstract excerpt
Molecular mechanisms regulating virus xenotropism and cross-species transmission are poorly understood. Host range mutants (MHV-H2) of mouse hepatitis virus (MHV) strains were isolated from mixed cultures containing progressively increasing concentrations of nonpermissive Syrian baby hamster kidney (BHK) cells and decreasing concentrations of permissive murine astrocytoma (DBT) cells. MHV-H2 was polytrophic,...
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