Article
Hearing loss due to the mitochondrial A1555G mutation in Italian families.
American journal of medical genetics - 12 Oct 1998
Casano R A, Bykhovskaya Y, Johnson D F, Hamon M, Torricelli F, Bigozzi M, Fischel-Ghodsian N
Abstract excerpt
Six Italian families with familial nonsyndromic hearing loss consistent with a maternal pattern of inheritance were analyzed for mitochondrial mutations. The three known mitochondrial mutations associated with nonsyndromic hearing loss were investigated by polymerase chain reaction amplification,...
Topics
- Adolescent
- Adult
- Age of Onset
- DNA, Mitochondrial
- Deafness
- Female
- Humans
- Italy
- Male
- Mitochondria
- Mutation
- Pedigree
- Polymerase Chain Reaction