Article
Sequence variation in the small-subunit rRNA gene of Plasmodium malariae and prevalence of isolates with the variant sequence in Sichuan, China.
Journal of clinical microbiology - 1 Nov 1998
Liu Q, Zhu S, Mizuno S, Kimura M, Liu P, Isomura S, Wang X, Kawamoto F
Abstract excerpt
By two PCR-based diagnostic methods, Plasmodium malariae infections have been rediscovered at two foci in the Sichuan province of China, a region where no cases of P. malariae have been officially reported for the last 2 decades. In addition, a variant form of P. malariae which has a deletion of 19 bp and seven substitutions of base pairs in the target sequence of the small-subunit (SSU) rRNA gene was detected...
Topics
- Animals
- Asia, Southeastern
- Base Sequence
- China
- DNA, Protozoan
- DNA, Ribosomal
- Genes, Protozoan
- Genetic Variation
- Humans
- Malaria
- Molecular Epidemiology