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Article

Comparison of phenotypic and genotypic methods for detection of diphtheria toxin among isolates of pathogenic corynebacteria.

Journal of clinical microbiology - 1 Nov 1998

Efstratiou A, Engler K H, Dawes C S, Sesardic D

Abstract excerpt

We have compared molecular, immunochemical, and cytotoxic assays for the detection of diphtheria toxin from 55 isolates of Corynebacterium diphtheriae and Corynebacterium ulcerans originally isolated in five different countries. The suitabilities and accuracies of these assays for the laboratory diagnosis of diphtheria were compared and evaluated against the "gold standard" in vivo methods. The in vivo and Vero...

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Identifiers

PMID: 9774560
DOI: 10.1128/JCM.36.11.3173-3177.1998
PMCID: PMC105296

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