Article
Neural basis of an inherited speech and language disorder.
Proceedings of the National Academy of Sciences of the United States of America - 13 Oct 1998
Vargha-Khadem F, Watkins K E, Price C J, Ashburner J, Alcock K J, Connelly A, Frackowiak R S, Friston K J, Pembrey M E, Mishkin M, Gadian D G, Passingham R E
Abstract excerpt
Investigation of the three-generation KE family, half of whose members are affected by a pronounced verbal dyspraxia, has led to identification of their core deficit as one involving sequential articulation and orofacial praxis. A positron emission tomography activation study revealed functional abnormalities in both cortical and subcortical motor-related areas of the frontal lobe, while quantitative analyses of...
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