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Article

Clusters of new identical mutants and the fate of underdominant mutations.

Genetica - 1 Jan 1998

Huai H, Woodruff R C

Abstract excerpt

Given favorable environmental and demographic conditions, premeiotic clusters of identical mutations can produce a broad distribution of the initial frequency of underdominant alleles. Because of these clusters, new underdominant mutations may not necessarily be as rare in a population as previously assumed. The fixation of underdominant mutations, especially those with low heterozygous fitness, is increased when...

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PMID: 9766962

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