Article
Detection of factor V leiden and prothrombin gene mutations in patients who died with thrombotic events.
Archives of pathology & laboratory medicine - 1 Oct 2002
Ranguelov Rostislav D, Rosenthal Nancy, Bromley Christine, Vasef Mohammad A
Abstract excerpt
CONTEXT: Individuals with factor V or prothrombin gene mutations are at increased risk for thrombotic events. Furthermore, the risk of recurrent deep venous thrombosis in heterozygous carriers of both factor V Leiden and prothrombin gene mutations is high enough that some investigators suggest lifelong warfarin prophylaxis for these individuals, even with a single spontaneous thrombotic event. OBJECTIVES: To...
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