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Article

Cardiovascular phenotyping in mice.

Cardiovascular research - 1 Jul 1998

Doevendans P A, Daemen M J, de Muinck E D, Smits J F

Abstract excerpt

Progress in molecular genetics has changed cardiovascular research. The mouse has turned out to be an invaluable model for mammalian genetic modifications to mimic and analyse cardiovascular pathology. Through the introduction of transgene and gene targeting technology, regulatory systems can be studied at the molecular level. Recent technical developments have down-sized the equipment for physiological...

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PMID: 9764188
DOI: 10.1016/s0008-6363(98)00073-x

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