Article
Differential lamina propria cell migration via basement membrane pores of inflammatory bowel disease mucosa.
Gastroenterology - 1 Oct 1998
McAlindon M E, Gray T, Galvin A, Sewell H F, Podolsky D K, Mahida Y R
Abstract excerpt
BACKGROUND & AIMS: In active inflammatory bowel disease (IBD), the intestinal mucosa is infiltrated by polymorphonuclear cells (PMNs), lymphocytes, and monocytes from the systemic circulation. Using an ex vivo model, we have investigated luminally directed migration of cells out of the lamina pro...
Topics
- Basement Membrane
- Cell Movement
- Cell Separation
- Female
- Flow Cytometry
- Humans
- Immunohistochemistry
- Inflammatory Bowel Diseases
- Intestinal Mucosa
- Male
- Microscopy, Electron
- Microscopy, Electron, Scanning
- Middle Aged
- Phenotype