Article
Aetiology of severe iron overload in a family with hereditary haemolytic anaemia.
British journal of haematology - 1 Sept 1998
Dykes A, Gürtler V, Firkin F
Abstract excerpt
Severe iron overload is a reported complication of certain erythroid disorders which are characterized by increased erythropoietic activity. Proposed mechanisms include enhancement of iron absorption secondary to increased erythroid activity and coexistent heterozygosity or homozygosity for haemochromatosis. We performed PCR-based analysis for the haemochromatosis-related HFE C282Y mutation in an extended family...
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