A simple screening test for variant transthyretins associated with familial transthyretin amyloidosis using isoelectric focusing.

doi:10.1016/s0925-4439(98)00037-4

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Article

A simple screening test for variant transthyretins associated with familial transthyretin amyloidosis using isoelectric focusing.

Biochimica et biophysica acta - 30 Sept 1998

Connors L H, Ericsson T, Skare J, Jones L A, Lewis W D, Skinner M

Abstract excerpt

Variant forms of the plasma protein transthyretin (TTR) are associated with the most frequently occurring type of familial systemic amyloidosis. Organ system involvement in transthyretin type amyloidosis (ATTR) is often similar to that which occurs in light chain amyloid disease (AL). The proper...

Topics

Amyloidosis
Family
Genetic Techniques
Humans
Isoelectric Focusing
Mutation
Prealbumin

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