Article
Expression status of BCL-6 and syndecan-1 identifies distinct histogenetic subtypes of Hodgkin's disease.
Blood - 1 Oct 1998
Carbone A, Gloghini A, Gaidano G, Franceschi S, Capello D, Drexler H G, Falini B, Dalla-Favera R
Abstract excerpt
The tumor cells in most cases of Hodgkin's disease (HD) have been recently recognized to originate from the B-cell lineage, but their precise differentiation stage is not fully clarified. Recently, we have reported that the histogenesis of B-cell lymphomas may be assessed by monitoring the expres...
Topics
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- CD40 Antigens
- CD40 Ligand
- Cell Differentiation
- DNA-Binding Proteins
- Embryonal Carcinoma Stem Cells
- Gene Expression Regulation, Neoplastic
- Germinal Center
- Herpesviridae Infections
- Herpesvirus 4, Human
- Hodgkin Disease
- Humans
- Membrane Glycoproteins