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Article

Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours.

British journal of cancer - 1 Sept 1998

Giarola M, Wells D, Mondini P, Pilotti S, Sala P, Azzarelli A, Bertario L, Pierotti M A, Delhanty J D, Radice P

Abstract excerpt

Desmoids are locally aggressive, non-metastasizing soft-tissue tumours, whose aetiology is still unclear. In patients affected with familial adenomatous polyposis (FAP), the incidence of desmoids is much higher than in the general population. The APC gene, which is responsible for FAP, is involved in the development of desmoids associated with this syndrome. In this study 16 sporadic and four FAP-related desmoids...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 9744495
DOI: 10.1038/bjc.1998.544
PMCID: PMC2063069

Genes

FAP
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours.PMID 9744495Read ↗

Desmoid tumors complicating Familial Adenomatous Polyposis: a meta-analysis mutation spectrum of affected individuals.Semantic proximity Read ↗

Desmoid tumour biology in patients with familial adenomatous polyposis coli.Semantic proximity Read ↗

A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor.Semantic proximity Read ↗

Desmoid Tumors in Familial Adenomatous PolyposisSemantic proximity Read ↗

3' Mutation of the APC gene and family history of FAP in a patient with apparently sporadic desmoid tumors.Semantic proximity Read ↗

Coexistence of somatic and germ-line mutations of APC gene in desmoid tumors from patients with familial adenomatous polyposis.Semantic proximity Read ↗

APC mosaicism in a young woman with desmoid type fibromatosis and familial adenomatous polyposis.Semantic proximity Read ↗

Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis.Semantic proximity Read ↗

Phenotype-genotype correlations in an extended family with adenomatosis coli and an unusual APC gene mutation.Semantic proximity Read ↗

APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.Semantic proximity Read ↗

Desmoid tumours in familial adenomatous polyposis.Semantic proximity Read ↗

Analysis of APC/beta-catenin genes mutations and Wnt signalling pathway in desmoid-type fibromatosis.Semantic proximity Read ↗

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