Article
High-dose (9 MU) long-term (60 weeks) alfa-interferon therapy for chronic hepatitis patients infected with HCV genotype 1b.
Archives of virology - 1 Jan 1998
Kanai K, Kako M, Kumada T, Tsubouchi H, Aikawa T, Kojima M, Harada H, Kawasaki T, Nakashima M, Okamoto H, Mishiro S
Abstract excerpt
Efficacy of standard regimens (e.g., 3-6 MU for 24 weeks) of alfa-IFN therapy for chronic hepatitis C has been limited, particularly in patients with HCV/1b. To see if higher-dose longer term treatment is more effective, we tried a 9 MU 60-week regimen. HCV/1b-infected chronic hepatitis patients received 9 MU IFN alpha 2a everyday but Sunday for 2 weeks and thrice a week for next 10 weeks, and 76 patients became...
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