Article
MTHFR association with arteriosclerotic vascular disease?
Human genetics - 1 Jul 1998
Fletcher O, Kessling A M
Abstract excerpt
Complex diseases are far more common than diseases that follow simple Mendelian patterns of inheritance. Difficulties are experienced in the designing of experiments to dissect out the contribution of a single allele to a complex phenotype. We review the literature regarding a point mutation in m...
Topics
- Alleles
- Arteriosclerosis
- Databases, Bibliographic
- Folic Acid
- Genetic Predisposition to Disease
- Homocysteine
- Homozygote
- Humans
- MEDLINE
- Methylenetetrahydrofolate Reductase (NADPH2)
- Oxidoreductases Acting on CH-NH Group Donors
- Point Mutation
