Article
Mortality among human immunodeficiency virus type 2-positive villagers in rural Guinea-Bissau is correlated with viral genotype.
Journal of virology - 1 Oct 1998
Grassly N C, Xiang Z, Ariyoshi K, Aaby P, Jensen H, Schim van der Loeff M, Dias F, Whittle H, Breuer J
Abstract excerpt
We present the results of a 6-year study of 131 human immunodeficiency virus (HIV) type 2 (HIV-2)-infected individuals from a rural population in Guinea-Bissau. Proviral DNA sequences 1.3 kb in length were obtained from each individual and, together with clinical data, including proviral load and CD4 and CD8 levels, were used to assess whether viral genotype influences clinical outcome. With a phylogenetic model,...
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