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Article

Mutations in a polycistronic nuclear gene associated with molybdenum cofactor deficiency.

Nature genetics - 1 Sept 1998

Reiss J, Cohen N, Dorche C, Mandel H, Mendel R R, Stallmeyer B, Zabot M T, Dierks T

Abstract excerpt

All molybdoenzymes other than nitrogenase require molybdopterin as a metal-binding cofactor. Several genes necessary for the synthesis of the molybdenum cofactor (MoCo) have been characterized in bacteria and plants. The proteins encoded by the Escherichia coli genes moaA and moaC catalyse the first steps in MoCo synthesis. The human homologues of these genes are therefore candidate genes for molybdenum cofactor...

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Identifiers

PMID: 9731530
DOI: 10.1038/1706

Genes

MOCS1

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Mutations in a polycistronic nuclear gene associated with molybdenum cofactor deficiency.PMID 9731530Read ↗

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A novel MOCS2 mutation reveals coordinated expression of the small and large subunit of molybdopterin synthase.Semantic proximity Read ↗

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