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Article

A novel MOCS2 mutation reveals coordinated expression of the small and large subunit of molybdopterin synthase.

Molecular genetics and metabolism - 1 Nov 2006

Hahnewald Rita, Leimkühler Silke, Vilaseca Antonia, Acquaviva-Bourdain Cecile, Lenz Ulrike, Reiss Jochen

Abstract excerpt

The small and large subunits of molybdopterin (MPT) synthase (MOCS2A and MOCS2B), are both encoded by the MOCS2 gene in overlapping and shifted open reading frames (ORFs), which is a highly unusual structure for eukaryotes. Theoretical analysis of genomic sequences suggested that the expression o...

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Source

Identifiers

PMID: 16737835
DOI: 10.1016/j.ymgme.2006.04.008

Genes

MOCS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16737835-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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