Article
Genetic linkage and cotransfer of a novel, vanB-containing transposon (Tn5382) and a low-affinity penicillin-binding protein 5 gene in a clinical vancomycin-resistant Enterococcus faecium isolate.
Journal of bacteriology - 1 Sept 1998
Carias L L, Rudin S D, Donskey C J, Rice L B
Abstract excerpt
Mechanisms for the intercellular transfer of VanB-type vancomycin resistance determinants and for the almost universal association of these determinants with those for high-level ampicillin resistance remain poorly defined. We report the discovery of Tn5382, a ca. 27-kb putative transposon encodi...
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- Base Sequence
- Carrier Proteins
- DNA Transposable Elements
- DNA, Bacterial
- Drug Resistance, Microbial
- Enterococcus faecium
- Genetic Linkage
- Hexosyltransferases
- Molecular Sequence Data
- Muramoylpentapeptide Carboxypeptidase
- Mutation