Article
A matter of life and cell death.
Science (New York, N.Y.) - 28 Aug 1998
Evan G, Littlewood T
Abstract excerpt
In multicellular organisms, mutations in somatic cells affecting critical genes that regulate cell proliferation and survival cause fatal cancers. Repair of the damage is one obvious option, although the relative inconsequence of individual cells in metazoans means that it is often a "safer" stra...
Topics
- Animals
- Apoptosis
- Cell Division
- Cell Survival
- DNA Damage
- Genes, Tumor Suppressor
- Humans
- Mutation
- Neoplasms
- Oncogene Proteins
- Oncogenes
- Tumor Suppressor Protein p53