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Article

The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococcus aureus.

Molecular microbiology - 1 Jul 1998

Lindsay J A, Ruzin A, Ross H F, Kurepina N, Novick R P

Abstract excerpt

Tst, the gene for toxic shock syndrome toxin-1 (TSST-1), is part of a 15.2 kb genetic element in Staphylococcus aureus that is absent in TSST-1-negative strains. The prototype, in RN4282, is flanked by a 17 nucleotide direct repeat and contains genes for a second possible superantigen toxin, a Dichelobacter nodosus VapE homologue and a putative integrase. It is readily transferred to a recA recipient, and it...

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PMID: 9720870
DOI: 10.1046/j.1365-2958.1998.00947.x

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