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Article

The molecular basis of inherited hypokalemic alkalosis: Bartter's and Gitelman's syndromes.

The American journal of physiology - 1 Nov 1996

Simon D B, Lifton R P

Abstract excerpt

Hypokalemic alkalosis with low blood pressure can be caused by a number of medications or alternatively as an autosomal recessive genetic trait. Molecular genetic approaches to this problem have recently demonstrated that mutations in genes encoding the thiazide-sensitive Na-Cl cotransporter or the bumetanide-sensitive Na-K-2Cl cotransporter produce two distinctive clinical and physiological pictures featuring...

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Identifiers

PMID: 8945989
DOI: 10.1152/ajprenal.1996.271.5.F961

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The molecular basis of inherited hypokalemic alkalosis: Bartter's and Gitelman's syndromes.PMID 8945989Read ↗

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Mutations in Na(K)Cl transporters in Gitelman's and Bartter's syndromes.Semantic proximity Read ↗

Molecular pathophysiology of Bartter's and Gitelman's syndromes.Semantic proximity Read ↗

Gitelman's variant of Barter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na–Cl cotransporterSemantic proximity Read ↗

Mutations in renal ion transporters cause Gitelman's and Bartter's syndromes of inherited hypokalemic alkalosis.Semantic proximity Read ↗

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Gitelman syndrome: pathophysiological and clinical aspects.Semantic proximity Read ↗

Bartter's and Gitelman's syndromes: from gene to clinic.Semantic proximity Read ↗

A novel mutation in the chloride channel gene, CLCNKB, as a cause of Gitelman and Bartter syndromes.Semantic proximity Read ↗

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