Article
Prevalence of deltaF508, G551D, G542X, and R553X mutations among cystic fibrosis patients in the North of Brazil.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 2005
Araújo F G de, Novaes F C, Santos N P C dos, Martins V C, Souza S M de, Santos S E B dos, Ribeiro-dos-Santos A K C
Abstract excerpt
Cystic fibrosis (CF) is the most common genetic disease among Caucasians and is rare among sub-Saharan Africans. The Brazilian population is not ethnically homogeneous but it is the result of three-way ethnic admixture of Europeans, Africans and Amerindians in varying proportions, depending on the region. In the present study, we investigated 33 patients who had been diagnosed and are currently under treatment...
Topics
- Brazil
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Electrophoresis, Polyacrylamide Gel
- Genetic Markers
- Humans
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Prevalence