Article
Evidence for increased synthesis of lipoprotein(a) in the nephrotic syndrome.
Journal of the American Society of Nephrology : JASN - 1 Aug 1998
De Sain-Van Der Velden M G, Reijngoud D J, Kaysen G A, Gadellaa M M, Voorbij H, Stellaard F, Koomans H A, Rabelink T J
Abstract excerpt
In patients with the nephrotic syndrome, markedly increased levels of lipoprotein(a) (Lp(a)) concentration have been frequently reported, and it has been suggested that this may contribute to the increased cardiovascular risk in these patients. The mechanism, however, is not clear. In the present study, in vivo fractional synthesis rate of Lp(a) was measured using incorporation of the stable isotope 13C valine....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.