Article
The apolipoprotein(a) size polymorphism is associated with nephrotic syndrome.
Kidney international - 1 Feb 2004
Kronenberg Florian, Lingenhel Arno, Lhotta Karl, Rantner Barbara, Kronenberg Martina F, König Paul, Thiery Joachim, Koch Michael, von Eckardstein Arnold, Dieplinger Hans
Abstract excerpt
BACKGROUND: The atherogenic serum lipoprotein(a) [Lp(a)] is significantly elevated in patients with nephrotic syndrome. The underlying mechanism for this elevation is poorly understood. METHODS: We investigated in 207 patients with nondiabetic nephrotic syndrome and 274 controls whether the apolipoprotein(a) [apo(a)] kringle-IV repeat polymorphism explains the elevated Lp(a) levels in these patients. RESULTS:...
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