Article
Isolation of mutants deficient in acetyl-CoA synthetase and a possible regulator of acetate induction in Aspergillus niger.
Microbiology (Reading, England) - 1 Jul 1998
Sealy-Lewis Heather M, Fairhurst Valerie
Abstract excerpt
Acetate-non-utilizing mutants in Aspergillus niger were selected by resistance to 1.2% propionate in the presence of 0.1% glucose. Mutants showing normal morphology fell into two complementation groups. One class of mutant lacked acetyl-CoA synthetase but had high levels of isocitrate lyase, whil...
Topics
- Acetate-CoA Ligase
- Aspergillus niger
- Cloning, Molecular
- Drug Resistance, Microbial
- Genes, Fungal
- Genes, Regulator
- Isocitrate Lyase
- Mutation
- Propionates
