Article
[Molecular biological background of FAP and HNPCC, and treatment strategies of both diseases depend upon genetic information].
Nihon Geka Gakkai zasshi - 1 Jun 1998
Baba S
Abstract excerpt
Recent advancement of molecular biology disclose responsible genes of FAP(familial adenomatous polyposis) and HNPCC(hereditary non polyposis colorectal cancer). Gardner Syndrome is now categorized as subtype of FAP. Turcot Syndrome is now known as a heterogeneous disease. Turcot Syndrome caused by APC gene develops medulloblastoma and Turcot Syndrome caused by mismatch repair gene develops glioblastoma. Because...
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