Single-Tube Polymerase Chain Reaction for Rapid Diagnosis of the Inversion Hotspot of Mutation in Hemophilia A

Abstract excerpt

To The Editor: Hemophilia A is the most common X-linked coagulation disorder, with an incidence of about one in 5,000 males. About half the families with severe disease have a large genomic inversion of the factor VIII gene that separates the first 22 exons from the final 4 exons. This inversion

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer-related gene regulation
• Share to Chronic Myeloid Leukemia Treatments
• Share to Hemophilia Treatment and Research