Glucose-6-phosphate dehydrogenase deficiency and homozygous sickle cell disease in Congo.

doi:10.1159/000022801

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Article

Glucose-6-phosphate dehydrogenase deficiency and homozygous sickle cell disease in Congo.

Human heredity - 1 Jan 2000

Bouanga J C, Mouélé R, Préhu C, Wajcman H, Feingold J, Galactéros F

Abstract excerpt

G6PD genotypes were determined in Brazzaville (Congo) on 188 HbSS patients (109 females, 79 males) and 210 controls (115 females and 95 males) with HbAA. DNA samples were analyzed by the polymerase chain reaction (PCR). The frequencies of G6PD B, A+ and A- alleles were 56.9, 20.8 and, 22.2% in th...

Topics

Adolescent
Adult
Age Factors
Anemia, Sickle Cell
Child
Child, Preschool
Congo
Female
Gene Frequency
Genotype
Glucosephosphate Dehydrogenase Deficiency
Hemoglobin A
Homozygote
Humans
Infant
Infant, Newborn
Male
Phenotype

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