Article
Glucose-6-phosphate dehydrogenase deficiency and homozygous sickle cell disease in Congo.
Human heredity - 1 Jan 2000
Bouanga J C, Mouélé R, Préhu C, Wajcman H, Feingold J, Galactéros F
Abstract excerpt
G6PD genotypes were determined in Brazzaville (Congo) on 188 HbSS patients (109 females, 79 males) and 210 controls (115 females and 95 males) with HbAA. DNA samples were analyzed by the polymerase chain reaction (PCR). The frequencies of G6PD B, A+ and A- alleles were 56.9, 20.8 and, 22.2% in the patients versus 56.3, 21.2 and, 22.5% in the controls, respectively. The prevalence of G6PD genotypes in HbSS did not...
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