Article
Genetic variation within the ovine cystic fibrosis transmembrane conductance regulator gene.
Mutation research - 1 May 1998
Tebbutt S J, Lakeman M B, Wilson-Wheeler J C, Hill D F
Abstract excerpt
We report here the results of a preliminary screening programme to identify natural mutations in the ovine cystic fibrosis transmembrane conductance regulator (CFTR) gene. Nine regions of the ovine CFTR gene were screened, corresponding to human CFTR gene exons 4, 6b, 7, 9, 10, 11, 12, 17b and 20. DNA samples from up to 2000 individual sheep were examined by single-stranded conformation polymorphism (SSCP) of...
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