An ovine CFTR variant as a putative cystic fibrosis causing mutation.

Abstract excerpt

This report describes a DNA variant in the ovine cystic fibrosis transmembrane conductance regulator (CFTR) gene that has been previously reported as a putative cystic fibrosis causing mutation in humans. The variant is a guanine to adenine base change at position 1019 of the ovine CFTR cDNA, cor...

Topics

• Animals
• Arginine
• Cystic Fibrosis
• Cystic Fibrosis Transmembrane Conductance Regulator
• DNA Primers
• Glutamine
• Lymphocytes
• Mutation
• Pedigree
• Polymerase Chain Reaction
• Polymorphism, Single-Stranded Conformational
• Sequence Analysis
• Sheep