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Article

Evolution of multigene families by gene duplication. A haploid model.

Genetics - 1 Aug 1998

Tachida H, Kuboyama T

Abstract excerpt

Evolution of multigene families by gene duplication and subsequent diversification is analyzed assuming a haploid model without interchromosomal crossing over. Chromosomes with more different genes are assumed to have higher fitness. Advantageous and deleterious mutations and duplication/deletion also affect the evolution, as in previous studies. In addition, negative selection on the total number of genes (copy...

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Identifiers

PMID: 9691065
DOI: 10.1093/genetics/149.4.2147
PMCID: PMC1460287

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