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Article

Testing natural selection vs. genetic drift in phenotypic evolution using quantitative trait locus data.

Genetics - 1 Aug 1998

Orr H A

Abstract excerpt

Evolutionary biologists have long sought a way to determine whether a phenotypic difference between two taxa was caused by natural selection or random genetic drift. Here I argue that data from quantitative trait locus (QTL) analyses can be used to test the null hypothesis of neutral phenotypic evolution. I propose a sign test that compares the observed number of plus and minus alleles in the "high line" with...

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Identifiers

PMID: 9691061
DOI: 10.1093/genetics/149.4.2099
PMCID: PMC1460271

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