Article
Resampling QTL effects in the QTL sign test leads to incongruous sensitivity to variance in effect size.
G3 (Bethesda, Md.) - 1 Aug 2012
Rice Daniel P, Townsend Jeffrey P
Abstract excerpt
Allelic effects at quantitative trait loci (QTL) between lineages are potentially informative for indicating the action of natural selection. The QTL Sign Test uses the number of + and - alleles observed in a QTL study to infer a history of selection. This test has been constructed to condition on the phenotypic difference between the two lines in question. By applying the test to QTL data simulated under...
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